Celery Seeds: New Studies 03/2026

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In human studies, celery is usually not examined as a “vegetable serving” but as a precisely dosed preparation made from celery seeds, to which the effects described here refer.

The reason is simple: dose and composition remain constant, making changes in measured outcomes easier to attribute.

Overall, findings have mainly pointed to effects on blood pressure and metabolic blood markers, and—in a combination product- to effects on symptoms of knee osteoarthritis.

Blood pressure

Lower values after celery seed intake. In a placebo-controlled clinical trial in adults with metabolic syndrome, celery seed was taken daily in a standardized dose for several weeks. By the end of the study, blood pressure values in the celery group were lower than at baseline.

Both measures were affected: systolic (upper value) and diastolic (lower value).

Vascular tone is also often cited as a plausible link: if blood vessels relax more easily and dilate, resistance in the vascular system decreases and blood pressure readings may improve. In addition, a possible role of fluid regulation is sometimes mentioned, because this can also influence pressure dynamics.

Blood lipids

In the same study, blood lipid markers were measured as well. In particular, a reduction in triglycerides and VLDL was reported. Both markers relate to “fat transport” in the blood and are often considered together when changes in lipid metabolism are discussed. In the results of this trial, these were the lipid markers showing a clear favorable signal in the celery group.

Blood glucose

Alongside blood pressure and blood lipids, glucose measures were also recorded. These also changed in a favorable direction in the celery group. Insulin and measures related to insulin action were assessed at the same time; for these, no clear difference was reported.

Uric acid

Another laboratory value that was lower after intake in the celery group was uric acid. In practice, this marker is often considered in the context of metabolic issues and was included among the laboratory outcomes in this study.

Knee osteoarthritis

In a randomized, placebo-controlled clinical trial in knee osteoarthritis, a pure celery product was not tested. Instead, a combination preparation of Boswellia serrata (frankincense) and celery seed extract was used. Pain, stiffness, and physical function were assessed.

Result: In the treatment group, pain decreased, stiffness improved, and everyday function improved.

In addition, the authors examined markers they discuss in relation to inflammation and cartilage metabolism. Here as well, favorable changes were observed alongside the improvements described above.

03.03.2026

Written by: Alireza Mohtashami

Sources:

[1] Effect of Celery Seed (Apium graveolens L.) Administration on the Components of Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion: A Clinical Trial. https://www.mdpi.com/1424-8247/19/1/110

[2] Efficacy and Safety of Boswellia serrata and Apium graveolens L. Extract Against Knee Osteoarthritis and Cartilage Degeneration: A Randomized, Double-blind, Placebo-Controlled Clinical Trial. https://pubmed.ncbi.nlm.nih.gov/39875757/